Mpox

Mpox is an exotic infectious disease caused by the Mpox virus. The disease was first identified in laboratory monkeys, thus earning its name, but in its natural state, it seems to infect rodents more than primates. A fever, headache, muscle pains, swollen lymph nodes, and fatigue are the first symptoms in humans. After this, a rash forms with blisters and crusts. Symptoms typically appear 7 to 14 days after exposure. In most cases, symptoms last 2 to 4 weeks. Children, pregnant women, and people with suppressed immune systems are at greater risk of severe cases.

Human Monkeypox – Epidemiology, Clinical Characteristics, Diagnosis, and Prevention

The human monkeypox virus, which belongs to the genus Orthopoxvirus of the family Poxviridae, is a DNA virus.

What is Monkeypox?

Monkeypox Epidemiology

Monkeypox 2003 U.S. Outbreak

Monkeypox; What is It and How Do We Treat It?

Latest Mpox News and Research

Mpox vaccine allocation targets 9 African countries

The Access and Allocation Mechanism (AAM) for mpox has allocated an initial 899 000 vaccine doses for 9 countries across the African region that are hit hard by the current mpox surge.

7 Nov 2024

WHO expands Emergency Use Listing for mpox diagnostics

As part of ongoing efforts to enhance quality-assured testing options, the World Health Organization (WHO) has listed two additional mpox in vitro diagnostics under its Emergency Use Listing (EUL) procedure.

30 Oct 2024

New initiative activated to strengthen response to mpox public health crisis

In October 2024, WHO and partners, in collaboration with Member States, activated the Global Health Emergency Corps (GHEC) for the first time to provide support to countries facing mpox outbreaks.

29 Oct 2024

African production of mpox vaccines could secure the continent’s health

As Africa grapples with multiple outbreaks of mpox, public health leaders say locally produced vaccines are vital to end donation dependence and secure the continent's health.

29 Oct 2024

Vaccination of young children could dramatically reduce mpox deaths in DRC

Vaccinating children under five-years-old in endemic mpox regions in the Democratic Republic of the Congo (DRC) would significantly reduce the number of deaths in the country, according to a new analysis by researchers at the Yale School of Public Health.

22 Oct 2024

New single-chain mRNA vaccines offer enhanced immunity and protection against mpox

Study reveals single-chain mRNA vaccines confer 100% protection against lethal mpox challenge in mice, marking a significant advancement in vaccine technology.

22 Oct 2024

New consortium launched to combat Mpox outbreak in Africa

University College Dublin (UCD) is leading MpoxVax AFRIVAC, a new €1.3 million international consortium that aims to rapidly deploy technology and develop new knowledge to end the current Mpox outbreak in the Democratic Republic of Congo (DRC) and surrounding countries.

17 Oct 2024

A review of clinical features, diagnosis, and management of Mpox

A comprehensive review in JAMA outlines monkeypox's clinical presentation and management, stressing the need for increased surveillance and vaccination efforts.

17 Oct 2024

Novel app enables surveillance of global travel-related illness

On around one in three trips someone falls ill, with gastrointestinal and respiratory complaints among the most common symptoms.

15 Oct 2024

FAU researchers highlight new vaccination barriers

Vaccines to prevent common and serious infectious diseases have had a greater impact on improving human health than any other medical advance of the 20th century, surpassing even sanitation and potable water. From the global eradication of smallpox in 1980 to the unprecedented development of effective and safe mRNA vaccines for COVID-19, vaccinations have played crucial roles in preventing millions of premature deaths and hospitalizations in adults and children.

8 Oct 2024

WHO lists first mpox in vitro diagnostic test under Emergency Use Listing

The World Health Organization (WHO) has listed the first mpox in vitro diagnostic (IVD) under its Emergency Use Listing (EUL) procedure, an important step in improving global access to mpox testing.

4 Oct 2024

New Health Impact Investment Platform launches to strengthen primary care

Execution is starting under the new Health Impact Investment Platform on the first country health investment plans turning original commitment into operational reality.

24 Sep 2024

Single dose of MVA-BN vaccine offers 58% protection against mpox

Researchers confirm the effectiveness of the modified vaccinia Ankara-Bavarian Nordic vaccine against mpox.

16 Sep 2024

NIH funds new research to combat emerging viruses

Albert Einstein College of Medicine has received a five-year, $14 million per year grant from the National Institute of Allergy and Infectious Diseases (NIAID) to participate in a broad national effort to develop "plug-and-play" vaccines and antibody-based therapies against a wide range of emerging viruses. The grant is part of NIAID's new Research and Development of Vaccines and Monoclonal Antibodies for Pandemic Preparedness (ReVAMPP) Network, which was announced earlier today.

14 Sep 2024

New mechanism aims to ensure equitable distribution of mpox vaccines and treatments

In coordination with Member States, the World Health Organization (WHO) and partners have established an access and allocation mechanism for mpox medical countermeasures including vaccines, treatments and diagnostic tests.

13 Sep 2024

WHO adds MVA-BN vaccine to prequalification list as first vaccine against mpox

The World Health Organization (WHO) has announced the MVA-BN vaccine as the first vaccine against mpox to be added to its prequalification list.

13 Sep 2024

Researchers find no evidence of monkeypox infection in pets, despite presence of viral DNA

Study found that MPXV DNA on pets in mpox-affected households was likely due to human contamination, not true infection, as no live virus or antibodies were detected.

12 Sep 2024

Avian influenza detected in Texas wastewater samples

Avian influenza A(H5N1) virus, which spread to cattle and infected 14 people this year, was detected using virome sequencing in the wastewater of 10 Texas cities by researchers at UTHealth Houston and Baylor College of Medicine.

12 Sep 2024

Single dose of MVA-BN vaccine shows 58% effectiveness against mpox

A single dose of the Modified vaccinia Ankara-Bavarian Nordic (MVA-BN) was 58% effective in protecting again mpox infection, according to a new study published in BMJ.

11 Sep 2024

Mpox inactivated in 60 seconds with Σ-MM™ & patient friendly collection swab

In the wake of the global Mpox outbreak in non-endemic countries in 2022, the medical community has been searching for safer and more efficient ways to transport and test virus samples, especially from patients in areas with limited biological containment facilities.

From Medical Wire 6 Sep 2024