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Targeting ferroptosis for overcoming chemoresistance in digestive tract tumors

The global burden of digestive tract tumors is profound, with these cancers accounting for nearly half of all malignant tumors worldwide.

8 Nov 2024

Advances in the surgical management of gastroschisis

Gastroschisis, a congenital abdominal wall defect, has transformed from a uniformly fatal condition to one with a 95% survival rate through surgical advancements over the past six decades.

8 Nov 2024

New study links genetic mosaicism to lower Alzheimer’s risk in adults with Down syndrome

Study finds mosaicism in Down syndrome reduces Alzheimer's risk, providing new insights into genetic influences on cognitive decline and dementia progression.

8 Nov 2024

Exploring mouse models for studying liver fibrosis regression

Liver fibrosis is a progressive and potentially reversible condition that results from chronic liver damage, which can be caused by a variety of factors, including metabolic dysfunction-associated steatotic liver disease (MASLD), alcohol abuse, and viral hepatitis.

8 Nov 2024

Key kinase involved in cell division linked to abnormal blood vessel growth in genetic disorder

Inhibition of CDK6 may prevent arteriovenous malformations in hereditary hemorrhagic telangiectasia by regulating endothelial cell cycle progression.

8 Nov 2024

Spatial transcriptomics uncovers tissue niches in multiple sclerosis

Mapping cell types in MS lesions reveals unique tissue niches and interactions, offering insights into the molecular drivers of multiple sclerosis progression.

8 Nov 2024

Link between COVID-19 and long-term risk of autoimmune and autoinflammatory connective tissue disorders

COVID-19 survivors may develop autoimmune conditions long-term, with risks varying by severity and vaccination status, necessitating continued health vigilance.

8 Nov 2024

Traditional Chinese herb shows promise against Alzheimer’s and Parkinson’s

Zizyphi spinosi semen demonstrates neuroprotective effects, improving cognitive function and reducing amyloid and tau pathology in models of aging and dementia.

8 Nov 2024

Research identifies best materials for long-lasting hip implants

Hip implants with a delta ceramic or oxidized zirconium head and highly crosslinked polyethylene liner or cup had the lowest risk of revision during the 15 years after surgery, a new study led by the University of Bristol has found.

8 Nov 2024

Gut bacteria changes may foreshadow rheumatoid arthritis

Changes in the gut microbiome before rheumatoid arthritis is developed could provide a window of opportunity for preventative treatments, new research suggests.

8 Nov 2024

Recruitment underway for a clinical trial testing new vaccine against respiratory viruses

Recruitment is underway for a clinical trial testing a vaccine candidate produced with The University of Queensland's molecular clamp technology against life-threatening respiratory viruses.

8 Nov 2024

Work-related stress linked to poor cardiovascular health

Research shows work-related stress negatively affects cardiovascular health, with implications for health behaviors and outcomes in diverse adult populations.

8 Nov 2024

California expanded Medi-Cal to unauthorized residents. The results are mixed.

California this year took the final step in opening Medi-Cal, its Medicaid program, to every eligible resident regardless of immigration status. It's a significant expansion for an already massive safety net program.

8 Nov 2024

Watchdog calls for tighter scrutiny of Medicare Advantage home visits

A new federal watchdog audit is ratcheting up pressure on government officials to crack down on billions of dollars in overcharges linked to Medicare Advantage home visits.

8 Nov 2024

Pregnancy vitamin D supplementation boosts bone density in kids up to age 7

Research indicates that vitamin D supplementation during pregnancy positively impacts children's bone health and lean mass, with potential long-term benefits.

8 Nov 2024

Age, education, and religion impact depression risk among Nigerian older adults

Research shows loneliness and physical inactivity are key factors in depression among Nigeria's older adults, emphasizing the importance of social interactions.

8 Nov 2024

Greener And Cleaner: Yeast-Green Algae Mix Improves Water Treatment

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8 Nov 2024

Understanding metabolic alterations and immune dysfunction in acute-on-chronic liver failure

Acute-on-chronic liver failure (ACLF) is a life-threatening condition characterized by acute deterioration of liver function in patients with pre-existing chronic liver disease.

8 Nov 2024

AI and imaging technologies transform pancreatic cancer diagnostics

Pancreatic cancer (PC) presents substantial diagnostic challenges due to its aggressive nature and lack of early symptoms, leading to late detection and poor prognosis.

8 Nov 2024

New research unravels mitochondria's role in breast cancer metastasis

Mitochondria have long been known as the tiny organelles that act as the battery packs inside our cells while also serving as internal sensors and communicators.

7 Nov 2024