It's official! Men and women experience and manage pain differently

Can't see this email? View it online

	Women's Health
	The latest women's health news from News Medical

	It's official! Men and women experience and manage pain differently Researchers uncover sex-specific pain management mechanisms, revealing men rely on endogenous opioids while women use alternative pathways for pain relief.

	Mediterranean diet lowers risk of multiple heart and metabolic diseases Adhering to the Mediterranean diet reduces the risk of developing a second cardiometabolic disease, especially over shorter follow-up periods, with social class influencing the diet’s impact.

			Everyday products ranked for health impact: Which ones are harming you and which are making you healthier? The Building H Index 2024 rates 75+ non-healthcare products on their impact on human health, identifying how daily-use items influence eating, sleep, physical activity, social interaction, and outdoor behaviors. The report pushes for company accountability in improving health outcomes through small product modifications.

			Frequent ultra-processed food consumption raises mortality risks, especially in women Ultra-processed food intake is linked to increased all-cause and cause-specific mortality, particularly in females, with metabolomic signatures highlighting the associated risks. This study provides critical evidence on the health dangers of UPFs.

			Excess body fat significantly increases risk of postmenopausal breast cancer Around 40% of postmenopausal hormone positive breast cancer cases may be linked to excess body fat, suggests Spanish research published online in the Journal of Epidemiology & Community Health.

	Understanding cardiovascular risks in endometriosis patients Endometriosis increases the risk of cardiovascular events.

	Genetic analysis shows smoking and high BMI increase dementia risk, but education and exercise protect Mendelian randomization of 400,000 participants reveals smoking, high BMI, and high cholesterol as major genetic risk factors for dementia, while longer education and physical activity reduce risks.

	Experimental drug RK-33 shows promise in treating breast cancer bone metastasis In a new study led by Johns Hopkins Medicine, the drug RK-33 has demonstrated promise in treating breast cancer that has spread to the bone (breast cancer bone metastasis). RK-33 was previously shown to help treat other types of cancer and viral illnesses.

	Beer consumption alters red blood cell lipid composition Moderate intake of both alcoholic and non-alcoholic beer causes mild changes in red blood cell membrane lipid composition without impacting membrane fluidity.

	New guidelines focus on preventing first strokes through healthy living Healthy lifestyle behaviors, such as good nutrition, smoking cessation and being physically active, along with routine health screenings and managing risk factors for cardiovascular disease and stroke with medication, can help prevent individuals from having a first stroke.

	Policymakers rethink diet-related interventions with a tool that focuses on lived realities Researchers propose a tool to help policymakers address dietary inequalities by considering people's lived realities, including economic, social, and material factors. This tool aims to improve the effectiveness of nutrition-related interventions.

	Experimental drug RK-33 shows promise in treating breast cancer bone metastasis Researchers estimate that expanding access to weight-loss drugs could save over 50,000 lives annually, reducing obesity rates and addressing health inequities. Current drug uptake levels prevent far fewer deaths.

	Study reveals emotional eating risks in middle-aged women with PCOS Emotional eating and uncontrolled eating are more common in middle-aged women diagnosed with polycystic ovary syndrome (PCOS).

	Can soda taxes fight obesity? New research adds to the debate Findings suggest the Philadelphia sweetened beverage tax may lower BMI and obesity prevalence in adults, offering insights into effective health interventions.

	FDA-approved breast cancer drug shows promise for appendix cancer Researchers at University of California San Diego School of Medicine found an FDA-approved drug used to treat breast cancer has the potential to be an effective therapeutic for a specific type of appendix cancer.

	Researchers uncover distinct cell vulnerabilities in Alzheimer’s progression with novel multiomics approach Researchers used single-cell and spatial genomics to map cell-type-specific changes in the middle temporal gyrus, identifying distinct disease phases in Alzheimer’s progression.

	Researchers identify shared genetic variants between testosterone traits and PCOS A genome-wide study reveals significant genetic overlap between polycystic ovary syndrome and testosterone-related traits, highlighting shared causal variants.

	Menopause transition linked to increased heart disease risk The risk of heart disease increases with age for most people, however, for women that may be even more true.

	Bright night light exposure increases mortality risk, while daylight reduces it Study reveals that brighter night light exposure and circadian rhythm disruption significantly increase the risk of mortality, particularly from cardiometabolic diseases, while brighter daytime light lowers these risks.