Neurology / Neuroscience - The Impact of Hormones on the Nervous System
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Application of Tau PFFs and Alpha-Synuclein PFFs in Neurodegenerative Disease ResearchApplication of Tau PFFs and Alpha-Synuclein PFFs in Neurodegenerative Disease Research

Pre-formed fibrils (PFFs) of tau and α-synuclein are essential tools for studying neurodegenerative diseases like Alzheimer's and Parkinson's. They mimic abnormal protein aggregation, enabling researchers to model disease progression. This application note provides detailed protocols for introducing PFFs into cell-based models, offering practical guidance for investigating protein aggregation and pathology development.

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   The Impact of Hormones on the Nervous SystemThe Impact of Hormones on the Nervous System
 
There are a number of key hormones which modulate the nervous system. Cortisol is a classic when discussing hormones and the nervous system. Cortisol is associated with the stress response, a biological change that occurs within the body when faced with a threat.
 
   Is There a Brain Microbiome?Is There a Brain Microbiome?
 
An emerging body of evidence suggests the presence of a brain microbiome
 
 Neuroimaging study reveals structural brain differences in children with autism
 
Neuroimaging study reveals structural brain differences in children with autismThere is new evidence that the cells responsible for communication in the brain may be structured differently in children with autism. Researchers at the Del Monte Institute for Neuroscience at the University of Rochester discovered that in some areas of the brain neuron density varies in children with autism when compared to the general population.
 
 
 University of Miami invests $30 million in neuroscience and aging research
 
University of Miami invests $30 million in neuroscience and aging researchDemonstrating its commitment to excellence as a member of the Association of American Universities and number one in the state for National Institutes of Health (NIH) funding, the University of Miami has pledged to invest more than $30 million to bolster basic science research that will target neuroscience and aging, some of the most complex conditions confronting the United States population, including in South Florida.
 
 
 Innovative brain simulation enhances understanding of neuron formation
 
Innovative brain simulation enhances understanding of neuron formationA new computer simulation of how our brains develop and grow neurons has been built by scientists from the University of Surrey.
 
 
 Replicating Lewy body formation in living neurons to understand Parkinson's disease
 
Replicating Lewy body formation in living neurons to understand Parkinson's diseaseLewy bodies are a hallmark of Parkinson's disease (PD) and other related neurological conditions. Understanding why and how they develop is critical to developing better treatments.
 
 
 Cholesterol imbalance linked to neurodegeneration, study suggests potential strategies for intervention
 
Cholesterol imbalance linked to neurodegeneration, study suggests potential strategies for interventionResearch highlights how cholesterol imbalances in the brain contribute to neurodegenerative diseases like Alzheimer's, Huntington's, and Parkinson's, suggesting targeted therapeutic interventions.
 
 
 WHO calls for urgent action on rising neurological conditions worldwide
 
WHO calls for urgent action on rising neurological conditions worldwideA major new study released by The Lancet Neurology shows that, in 2021, more than 3 billion people worldwide were living with a neurological condition.
 
 
 Neuroscientists uncover brainwave dynamics in memory storage
 
Neuroscientists uncover brainwave dynamics in memory storageIn the space of just a few seconds, a person walking down a city block might check their phone, yawn, worry about making rent, and adjust their path to avoid a puddle.
 
 
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