Cardiovascular disease pathways associated with psoriasis, but not other immune-mediated diseases

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	Rheumatology
	The latest rheumatology news from News Medical

	Cardiovascular disease pathways associated with psoriasis, but not other immune-mediated diseases A genetic connection between cardiovascular disease and psoriasis highlights shared inflammatory pathways, emphasizing the need for cardiovascular monitoring.

	Microbial biomarkers identified in lupus and IBD offer pathways for targeted therapies Research connects gut microbiota to lupus and IBD, uncovering microbial markers and pathways that could inform targeted therapies for autoimmune disorders.

			Mechanically stimulated 3D multicellular systems To study biomechanical forces in multicellular systems, effective mechanical stimulation is an essential tool. A 3D microstructure device is developed using Two-Photon Polymerization (2PP)-based 3D printing for mimicking the human multicellular environment.

			Researchers gain new understanding of how immune cells respond to heat during fever The study reveals that moderate fever enhances CD4 T cell activity while reducing regulatory T cell suppression, highlighting temperature's immune effects.

			Study highlights limited evidence for antidepressants in treating pain in older adults University of Sydney research has found people over 65 are being prescribed antidepressants as pain treatment based on international guidelines that use limited evidence.

	Philanthropic investment establishes research center to advance precision diagnosis for diseases An outstanding $21 million philanthropic investment will establish a pioneering research center to advance precision diagnosis for diseases that affect millions of Australians.

	'Treating Naturally Occurring Disease’, explained by Founder, Professor Noel Fitzpatrick Humanimal Trust advocates for studying naturally occurring diseases in animals to advance cancer and osteoarthritis treatments for both humans and animals.

	Steritas' Pediatric Glucocorticoid Toxicity Index applied in clinical trial to assess steroid-toxicity Steritas LLC.

	Premature ovarian insufficiency in women linked to greater risk of severe autoimmune conditions Severe autoimmune conditions such Type I diabetes, Addison's disease, lupus and inflammatory bowel disease, are between two to three times more common in women who have been diagnosed with premature ovarian insufficiency (POI) compared to the general population.

	Study highlights potential for targeting macrophages to improve rheumatoid arthritis outcomes Currently there are no cures for rheumatoid arthritis (RA) which affects 40,000 people in Ireland. The disease costs an estimated €20,000 per patient, per year with an overall cost to the health system of ~€544 million.

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